Electron Transport Chain vs Oxidative Phosphorylation

	oxidative phosphorylation	electron transport chain
energy input / usage	utilizes products of the Krebs cycle	driven by the process of proton pumping by complexes I, III, and IV
phosphorylation / dephosphorylation	generates ATP from energy stored by the electron transport chain (ETS)	consumes NADPH & FADH2
proton pump	ultimately coupled to phosphorylation	electron transport is driven by the proximity of reduced and oxidized carriers generated by proton pumping
electron transport	complexes I, III, and IV pump protons coupled to proton pumping ... you don't get one without the other	electrons enter the chain only through NADH dehydrogenase and succinate dehydrogenase electron transport is driven by the proximity of reduced and oxidized carriers generated by proton pumping
chemiosmotic gradient	maintained in presence of substrate, and in absence of mitochondrial poisoning by chemicals such as cyanide ATP synthase protons do not reduce O2, which acts as an electron acceptor	ETS accepts energy from carriers in the matrix the ETS moves electrons because of the chemiosmotic gradient
ATP synthase	membrane-bound enzyme at final step in oxidative phosphorylation	follows from and is not part of the electron transport chain
ATP synthase activation	does not alter the chemiosmotic gradient	ETS maintains the gradient at a constant level ATP synthase activation increases the rate at which energy is removed from the gradient
O2 consumption	ATP is not needed for O2 consumption	O2 serves as an electron acceptor, so the electron transport chain drives O2 consumption

Adapted from here.