Enzymes Cofactors of Krebs Cycle

Enzyme	Cofactors	Inhibitors	DG(kcal/mol)
citrate synthase			-9.1
aconitase		fluorocitrate	+1.6
isocitrate dehydrogenase	NADP+		-1.7
a-ketoglutarate dehydrogenase	NAD+, FAD, lipoate	arsenite	-8.8
succinic thiokinase	ATP	hydroxylamine	-2.1
succinate dehydrogenase	FAD, FeS group	malonate	0
fumarase		meso-tartrate	-0.9
malate dehydrogenase	NAD+	b-fluoroxalacetate fluoromalate	+6.7